Yeah, that's a HUGE difference in location and amenities. Massive.
You'd lose the use of Magical Express, Extra Magic Hours, the early booking of FP+ through
MDE, early access to ADRs. You'd be going from a Disney-operated deluxe resort that's in the center of WDW, in easy walking distance to two theme parks and the Boardwalk, to a rather generic hotel that's on the edge of the property. Near Disney Springs, yes, but it's not on the Disney transportation system. The hotel does operate a shuttle, but it's not nearly as frequent or convenient as the Disney system. If you were planning on driving to the theme parks, you'll have to pay the full daily parking fee. Guests of Disney resorts get free parking.
Oh, and the pool. Stormalong Bay.
Don't get me wrong, the Disney Springs hotels are perfectly good hotels, and they're absolutely more budget-friendly than a Disney deluxe. If none of the amenities/perks I mentioned above are of use to your group, then they're certainly worth considering.
ETA: I just looked at your signature, and see that you've stayed at the Doubletree before, as well as Disney resorts, so you're aware of the differences.