This has always been an interesting question in our family! I don't think length of flight matters. My spouse is always aisle - easy in and out, doesn't get that claustrophobic feeling sitting inside by the window, has a smidge more leg room flexibility. I've always been window - no matter how many times I fly, I like being able to look out the window and see the world! Of course that doesn't help much during nighttime flights, but I still prefer it. In a 3-seat configuration when it's 2 of us flying, I always end up in the middle, because the aisle seat is the priority in this family!!! And I'm good with that!!