I think the best area would be Hollywood & Highland where Mann's Chinese Theater is located. You will also see the famous hand/footprints and more famous stars. There are some restaurants at the Kodak Theater center, and if you walk up the stairs to the back you can see the Hollywood sign. It's where most people go. Under that complex is a parking structure. I've been there a number of times, and during the day would be the best time to go.
Across the street is Disney's El Capitan Theater and where Jimmy Kimmel does his show.