Lots of famous people lived in Ann Arbor at one point in their lives
A few notables:
-Former US President Gerald Ford
-Madonna
-Bob Seger (went to the same middle school I did, albeit a few years earlier than I)
-George Frayne and John Tichy (2 original members of "Commander Cody and his Lost Planet Airmen")
-Folk singer Katie Geddes
-Professional athletes, including a 2-time super bowl MVP (Tom Brady), Charles Woodson, Desmond Howard, Jim Harbaugh (also went to the same middle school that I did), Brendan Morrison, Rudy Tomjonavich, and others
-Astronaut Jack Lousma
-Ken Burns
Aside from the famous people, Ann Arbor also has a pretty decent-sized university, and a large Pfizer research facility (Lipitor was developed in Ann Arbor, as was Viagra, I belive), and one of the largest art fairs in the nation.