This has been a fun thread to read because we also have a rescue dog with issues. We are the "emotional support humans" to our terrier. She is doing very well on Prozac. We've had her almost three years and she still won't play in the backyard. The first year she'd only walk the perimeter. Now she'll sniff around, but if you try throwing her a toy she looks at it like - what? She still doesn't play and gets upset and frightened if other dogs or people try to get her to. She loves to go places with us, but we have to be sure she always wears her harness and leash because if she sees someone who scares her she can jump right out of her collar and RUN for her life.