Hi -
I have not been to Ripley's, but went to Wonderworks another day after we had been to the Orlando Science Center.
Science Center is cleaner, cheaper, has IMAX, more diverse age-appropriate activities ( 5 floors!) and duplcates many of the hands-on activities at Wonderworks. We did OSC first, after that, I felt that Wonderworks was a rip-off. Somed parts felt crowded, cheesy and worn.
Then again - that building on an angle is something to be seen.
JMHO! Good luck and enjoy!!!