Cafe TuTu Tango on I-Drive, south of Sand Lake is eclectic and fun featuring a sort of tapas style menu served in an active "artist's loft" setting. Good food, good drinks for the adults and lots to keep the kids occupied.
For Thai in a beautiful setting, Thai Thani at the intersection of Central Florida Parkway and I-Drive is very enjoyable. It is about a 10 minute drive from Universal if you take Turkey Lake to Central Florida. They also have a new location in downtown Celebration but that is further away.
For Thai in a minimalist setting, G G at the intersection of Turkey Lake and Conroy is quite good. Not as ornate in terms of decor, but good food.
I second the recommendation for Agave Azul at the intersection of Kirkman and Conroy. Good food and very yummy maragaritas.
Alehouse is always a good option for basic food and drink in a casual, sports bar type setting. However, I think you'd do better to visit the newer location on I-Drive near Wonderworks versus the Kirkman location. This might be a good alternative to a "bottom feeder" location like a (blech) CiCi's Pizza
For something a bit more upscale, Seasons 52 if always a good choice. Fresh market inspired cuisine with a menu that changes seasonally to take advantage of the best and freshest ingredients. They are located on Sand Lake Rd's restaurant row.
Oh, and if you are yearning for REAL bagels one morning, take a run to Delish NY Bakery in the Whole Foods plaza at the intersection of Sand Lake and Turkey Lake. You can get sandwiches, knishes or really yummy sweet treats there as well.
Everything I've mentioned should be no more than 15 minutes from your hotel.