I know it has already been said, but its worth saying again. Make sure your fridge is working properly. I use Enbrel - which also requires refrigeration. When we first got to our room, the fridge did not feel very cold. The back panel of the fridge was pushed out on one side. Once my hubby fixed that, the fridge seemed to work OK. I will bring a thermometer in the future - just for my own piece of mind - to ensure that my meds are stored at the right temp.