My wife and I just returned from POFQ April 2-6. It was our first time staying there and we LOVED it. Living only 90 mins from New Orleans and having visited NO many times, POFQ does a great job of capturing the look and feel of the French Quater-minus the smell and drunks on the street. We stayed in 4220 I think. It was a parking lot view room. We were 5 mins from the bus stop, pool, and food court. If they do prefered rooms I would guess they are the ones overlooking the river running behind the resort. If you will enjoy the view, which is fantastic, it may be worth it. But you will have to walk to the front of the resort for the bus and food court. Either way though its not a far walk.
Hope you enjoy it as much as we did.