Forget picking a bag to carry all day! Just carry the camera itself, on a comfortable strap of some kind, and leave the bag in your room.
The only thing a camera can take pics of when it's in a bag is the inside of the bag. And while the inside of a camera bag may be a fine place, I have no burning desire to start a collection of pics of them. But I do have a burning desire to take pics of my vacation experiences, which is why my camera stays out and ready at all times when I'm touring - turned on, lens hood in place, lens cap off. I do have it set to go into sleep mode after about 3 minutes, to save battery power.