Why did we purchase a Toyota over a Honda? We thought the Honda was uncomfortable - it seemed more rigid to us.
This was what we found as well - the Honda seats were not comfy at all.
We're currently on our second Toyota Sienna LE. The first was a 3 year lease that we just turned in about a month ago and then we purchased a 2009 model.
We previously had a Dodge Caravan and a Dodge Grand Caravan - both of those felt like they were going to fall apart when they were about 2½-3 years old.
The Toyota we just turned in was still great - about the only "aging" I noticed was there were some squeaks and groans in the interior - dash rattle and such. I wanted to keep it, but to buy it at the end of the lease would have been almost as much as buying a new one, so DH went with buying a new one.
... I am an odd one and didn't want the power doors so that was another reason I wanted the lower model. I just personally don't like them.
I don't think you can go wrong with either brand, but I do think both have their strengths and weaknesses.I was lucky enough to get my dream minivan 2 years ago.
T&C, stow and go, with DVD player. IT has come in so handy with moving and trips home.

We had a 1997 Oldsmobile van that had power doors. It was one of the first things to die on that poor van. And, it was going to cost a small fortune to replace. I vowed to not have power doors from that time on. I'm sure it's the same as having power windows, but it's not even a possibility to have roll down windows anymore! The more bells and whistles you have, the more things you have to fall apart!