We drove from OKC to WDW in November. We had two cars, 12 people and drove thru the night. The getting there wasn't too bad but the drive home seem to take forever. 1400 miles one way.
Just my family has driven that trip too many times to count and we usually leave very early from OKC and try to get all the way to Penesecola the first day so that the next day is much shorter.
We love to fly, but the cost difference stops us most of the time. And we really like having our car available to us also because we mostly stay off-site.
I'm always on the look out for airline deals. There is supposed to be a new straight thru flight from OKC to Orlando Sanford Airport with Trans Meridian starting February 11 on Wednesdays and Saturdays.
Good Luck!
vgsmom