Which way are you planning on going? The Chesapeake Bay Bridge Tunnel will add $12 each way to your trip but save you time and most likely a headache.
I live in Norfolk and drive "home" (my parents house) to just north of Albany, NY about once/twice a year. The Chesapeake Bay Bridge Tunnel will save you about 95 miles and makes the trip so much more enjoyable. Just watch your speedometer on Rte 13! There are a lot of small towns that are speed traps.
I'd say it's about $10-$12 from NY to the Bridge Tunnel (ie you completely bypass NYC and don't pay any of those pesky bridge tolls). The Del Mem Bridge is $3 Southbound, but nothing Northbound as far as I remember. If you add the tunnel, it's $12 more, and if you take Rte 1 instead of 13 in Delaware (which I HIGHLY recommend) that will add $2-$4 depending on if you're driving on a weekday or weekend.
Have fun making the trip! I know it well