Bonine (Meclizine) is an antihistamine that is used for vertigo, sea sickness, and meniere's disease. All of these conditions are caused by a middle ear pressure imbalance. For Seasickness prevention, one dose per day is probably sufficient. It can be taken up to 25mg every 8 hours if necessary. That is where the drowsiness can become more evident. If you know you always get seasick, it will work better taken as a preventative, than after the fact. Dramamine (dimenhydrinate) is also an antihistamine that is specific for treating middle ear imbalances. It will generally cause more drowsiness, than Bonine (Meclizine). Meclizine should only be taken by adults > 12yrs of age. Dramamine can be dosed in younger children, but the liquid is no longer available. A chewable tablet is available for younger children. Dramamine is available in a "less drowsy" formula, but if you look at the ingredients it is meclizine. You may get some benefit by taking other types of antihistamines, but none will work as well as Bonine or Dramamine. If you take an anthistiamine for allergy symptoms on a daily basis, you can take Bonine (Meclizine) for seasickness, but be aware of side effects such as drowsiness, tiredness and dry mouth Everyone is different in how they react to antihistamine sedation. Some people will even get drowsy from the non-sedating antihistamines such as Claritin, Allegra etc. These products will generally not aggravate patients with high blood pressure (although that will vary with the cause of their high blood pressure), but can cause problems with people that have prostrate problems & glaucoma