I'm assuming that you are wanting to do a budget trip. Some of the nicer places in the area can be pricey. My BFF and I went for a girls weekend and she'd never been before, we we stayed at a place on Bourbon Street. The name escapes me, but my BFF wanted someplace with the "feel" of New Orleans. With the balconies and cool architecture, central location, yet inexpensive. We thought we found the perfect place. I arrived before her and the place was pretty run down. Sinking, uneven floors, older furnishings. Balcony was iffy at best. When she got there, we got a big laugh out of it since the pics on the website were obviously very old ones! But if the place was clean, we would be fine.
Unfortunately, cleanliness was an issue. The sheets on the bed had pubic hairs on them. We complained and they moved us to a different room. That room still had trash in the trashcan, also had dirty sheets, and was worse then the first one. We complained again, and they moved us to one of their "suites". There were roaches on the wall when we walked in, the sheets also had pubic hair on the main bed, the rollaway bed had urine stained sheets on it, and there were mouse droppings under the sofa cushions. At that point, the management told us that we were being "too picky".
So, in the middle of the night, we were scrambling to find lodging and we stayed at the Ramada on Bourbon. It was $30 more per night then the other place but it was WONDERFUL!! It had a gorgeous courtyard with that New Orleans feel to it, private parking (much better then the scary parking garage we had to park in at the first place), great location, it was CLEAN, and had a very nice free breakfast! And the people were very nice to us there! Waaay worth the extra cost and, to be honest, we probably could have gotten a better deal if we'd booked there ahead of time.
So, be wary of the local budget hotels. They seem like they would be charming, but some of them are scary! We had tried to stay away from the chain hotels, but we were so pleased with the Ramada. If I were to ever go back, I would stay there again in a heartbeat!