I haven't read through all the responses, so I'm sure others have said this, but my two cents is this:
It's time they do their own laundry.
Your job, as the parent, is to teach them to 100% be able to live independently away from you. They need to work that muscle way before they actually leave.
Have a family meeting, explain this, teach them, print instructions on how to do laundry. Give them a basket.
But after this, the clothes that are tossed on the floor are picked up by you. And then hidden away.
"Mom, where is my "fill in the blank"?
You: "Its in clothes jail for 2 weeks. Every time a piece of clothing is on the floor, or anywhere not on your body, in a drawer, a hanger, or the dirty clothes basket, it is picked up by me and stored away."
This is the hard part of parenting.
It's called consequences. But in the end you'll be doing them a huge life favor, doing their future spouses a favor, and giving them a model to help their own kids one day.
You can do this.