What type of problem are you having?
Just not showing up or is MDE not working right at all?
I know I (and others) have problems with Chrome. All we get is a white page, or it loops and reloads but nothing ever shows up. Nothing will fix it, clearing cookies, etc. However, it does work when you go Incognito. Which leads me to believe that for some reason the website errors when it tries to store cookies on your PC.