We spoke mainly to the planning office, but also to a member of the RPC concierge team, who I think became our advocate and ensured that our requests were met. She saw that 4422 became available before we arrived and she told us that she held it for us. We called the planners and reminded them frequently about our requests, especially the desmoking. Their attitude was always, "we'll see what we can do" or "we cannot guarantee anything." Not too reassuring, so we called alot.
Regarding the room, IMHO 4422 is the best deluxe. The floor plans are on the FAQ here and on Disney's site. 4419 and 4420 are deluxes, but the view is awful (inside courtyard where the old pool is located). Those rooms are basically oversized hotel rooms, and 4419 is handicapped equipped, so there is no tub. 4422 and 4426 (I think it is 26) are the other floor plan, which I think is better, and the view from 22 is great. 26 faces the monorail. The same rooms are on the third floor, but that is the floor where the band is, and noise can be an issue. I hope these comments help!