Thursday nights haven't really been claimed by anyone as far as I know. There is a blog dedicated to listing clubs in the area with the same style of music as the clubs on PI. For LGBT, Mr Sister's is the big place right now on tues, fri, and Sat. Phouse is fun on Sundays also. For gay days, they do "PI at PH" and compeltely harp on the PI thing. This year they did the mannequins phantom of hte opera show, countodwn to NYE, fireworks, and that flashlight show that was done at one point on PI. They even had "PH Live" and an amazing sound and lighting system outside. The bass pounded like MDP.
edit: http://orlandoclublist.blogspot.com/ is the blog. He tends to list the straight clubs primarly, although I did bug him to put Mr Sisters on there under MDP recomendations