United, American, and Delta are the only major carriers out of our homewtown airport.

In 2 years we're looking to fly to Seattle or Vancouver and take an Alaskan cruise.
I don't have loyalty to any of these carriers, but I'd like to start working towards some big savings on this 2021 trip. Any advice on which way to go? I do have Chase UR and could use them for this trip. Perhaps the best strategy is to keep plugging away at those? I have quite a bit of organic spending (especially if using Plastiq) so I could potentially earn quite a few larger bonuses.
We don't have loyalty to a particular cruise brand either. I personally want to take a
Disney cruise, but my uncle and cousin's family is planning to go as well, and I'm certain they won't want to pay more for Disney. (However, this year there was a military Disney cruise discount last minute, and if these other family's plans fall-out, I would be tempted to wait-and-see what becomes available, if anything.