This a very difficult and personal decision for you to make. I hope that our posts are giving you some things to think about and some insight for those of use who have followed wherever our partner has lead us. Let me share my story.
My first time away from home took me out of the country! That was a culture shock to say the least! I missed EVERYONE and EVERYTHING! My sister in law took the time to go around town with a video camera and filmed our family members at work, went to coffee with friends, etc and sent it to us. I wore that tape out! I was able to find work. I missed my family and friends dearly. This was before the internet boom and the phone was very expensive. Snail mail was my dearest friend.
I look at each move as a form of growth for myself and my family. I have the benefit of the having the mindset that if I don't like a particular place, I know it's not forever. We will soon be on the move again. We've never been in any one place for more than three years over the past 18 years. Some jobs my DH enjoys and he's happy, others not so much and he can't wait to be on the go again. I made the personal choice to follow this man. Someday we will settle down and live where it's always warm and I can throw away all the boxes that my electronics originally came in.

We will live in a house that we took the time to find not the "hurry up and find a place" kind of home. But it's always fun/frustrating putting a house together and finding there isn't enough space for your existing stuff or the house is bigger than the stuff you have. It's all good and all part of the adventure.
It's all scary, exciting, joyful, stressful. Moving is taxing on oneself as well as a relationship. But we've made it work and I hope that it does for you as well.
My mom and I are very close as well. She looks at our various locales as an adventure for herself. Without us moving, she says she'd never get to see the country. She's been everywhere we've been, except Europe (one she shouldn't have missed!) She enjoys the travel. We enjoy "just us" time when she comes, as I usually take time off for her visit. We still talk on the phone almost daily.
I hope that you take some good time for self reflection and talk openly with your partner. It's a big change for both of you. Be open with your feelings and keep your pro/con list going.
Good luck!