I'd go Hyatt.
The North Tower is impeccable. The Hyatt is the first stop on the shuttle route which uses full-sized busses and not the silly little trollies.
The rooms are very clean with french doors separating the living space and the bedroom area. Each room has a fridge. We had a Kid Suite which had bunkbeds in a separate room (instead of a sleeping area), but both rooms had TVs.
The staff is very efficient and helpful. The bellhops offer tons of information on your way up to the room and give you a nice orientation of your room, including points of interest in the view from your room. Our corner room caught the top of the Sun Wheel and Maliboomer at DCA as well as Edison International Field, The Big A, and the Crystal Cathedral.
The hotel is primarily a businees-oriented property, so the prices in the restaurants are steep. The only real drawback to the place is the parking, which I believe we paid $14/night for valet (but we never waited more than 2-3 minutes for them to retrieve our car).
Avoid the hotel restaurant infavor of all the nearby restaurants (Red Robin, Outback, Joe's Crabshack). There is a Target within walking distance.