That's almost impossible to answer these days! Weather in Orlando, weather at your destination, weather around the country (depending where your plane is coming from), mechanical issues - all can throw a monkey wrench into the mix at an airport as busy as Orlando. There are the same delay risks at MCO as you might find at Atlanta, Chicago, JFK, etc. We've always found it better to fly out in the morning or at least early afternoon from MCO, before the delays can accumulate.