It depends on what you plan to do with them.
1. If you plan to use them to hang from a back pack I'd either cut them out or simple carefully pull them off the backing. The office section in Wal Mart has some self laminating sheets, luggage tags, etc. Glue the Mickey Heads together with either plain Elmer's glue or a glue stick, let dry, write your name (or screen name) on them with a permanent marker, if you want you can decorate them with some little Disney stickers and/or glitter, again let dry, then laminate them using the lagguage tags laminating film, put the plastic strap (come with the laminating set) through the laminated luggage tag, then attach the other end to your backpack. Note: make sure you buy the self laminating tags, not the ones that require a machine.
2. If you're using the Mickey Heads for a garland for your room window or door, just glue them back to back in pairs, punch a hole through them, and string them on a 1/4" wide ribbon tying off each head as you string them-no need to laminate, then simply tape them to your room window or door.
3. If you just plan to use them to decorate the window individually, just cut them out and tape them to the window. Again no need to laminate them.
4. If you plan to use them to decorate your room door, cut them out and stick a small piece of magnetic strip to the back to stick on the door. You may or may not want to laminate them. I usually don't, but they may curl a little around the edges, by the end of the week.