Hilton Head Thrift Shops
On Hilton Head Island there is the My Sister's Closet Consignment shop on HW278 down toward Sea Pines Circle.
There is the Gullah Flea Market just as you get on the Island (near the turnoff to Hudson's Seafoods), also on HW278 and full of Junk, but tastes different. It's a big long white building.
There is a Goodwill store by Sam's Club.
There is a St. Francis Thrift Store on HW278, can't remember the address.
There are a couple of antique stores, and consignment shops around the corner from My Sister's Closet, go toward Sea Pines and take the first right.
The Library has used book for sale and art work by local artists.
If you go toward the toll bridge from Sea Pines Circle there are two consignment shops to the right before you get to the post office - I think one is called Grannie's Attic (not sure).
The Bargin Box is a rumage sale sponsored by the Presbyterian Church on HW278 down about the turn of the island. It is open on M-W-F from 2 to 4 PM I think. This is a major event and you have to get in line to get in. They only let about 100 people in the building at a time, and as one comes out, one is let in. Two out - two in etc.
Hope this helps.