I live in baltimore and my father in law is a lifetime prosecutor in the city. Unless you plan on participating in the drug trade or gang wars, you won't encounter any crime. Baltimore has a huge drug/gang problem (if you've seen the show, the wire you'll be familiar with it) and almost 99% of the inner city violent crime is drug related...says my FIL. But still have your wits about you as you would in any crowded place or city bc petty theft can happen anywhere. The major crime areas of the city are not inner harbor adjacent. You will probably encounter people asking for money, but that's all.