No you don't. At least not if you respect the person.
She didn't say he told her SHE couldn't go, just that HE has no interest in cruising, ever. She can go on the cruise with the fam, he can stay home. It's called respecting one's decision to not do something, especially if it's been stated many times that they DO NOT want to do it. Ever. Respect his decision.
You can respect a spouse while asking them to compromise on a personal preference or experience some temporary discomfort. Obviously there are lines that can't be crossed--for example, you can't compel a spouse to compromise on their deep seated principles like religious belief, or about childbearing (though actually, maybe even those aren't great examples since I know couples that have compromised on both those things for each other, and that compromise was a testament to their respect for each other, not the opposite). Marriage is full of compromises on everything big and small, from careers, to where you live, to expenses you incur, to how you raise your kids, to lwhose family we're spending the holidays with. If my husband and I never compromised, we'd never go on a family vacation together. For example, I absolutely hate the outdoors, yet I went to a national park and got covered in mosquito bites and hike miles in 100 degree weather and hated every second of that, but my husband compromised by instead of camping, booking a nice resort outside the park so I could come back to a nice restaurant dinner and a soak in the hot tub. He got something that was important to him, and I don't resent him for that, and I wouldn't be respecting him if I took away from his opportunity to have a family vacation in a place he really wanted. He goes on plenty of disney trips for me even though it's not his preferred kind of vacation, but I make compromises for him on those too. OP's husband is just refusing to compromise even though as discussed in this thread there a lot of things they can do to mitigate his concerns--trying medication, booking a shorter cruise, finding a cruise with lots of port stops to minimize time at sea, booking a midship/low cabin. I don't think saying "never" means you are respecting your spouse, and I don't think a spouse should be required to never question or push another spouse beyond their comfort zone. As they teach our kids in schools these days, that's a closed mindset.
Low risk of severe side effects does not mean equivalent efficacy. Efficacy is how well a medication works for that individual.
Bonine is not efficacious for me; no particular negative side effects it simply doesn't alleviate the motion sickness. Dramamine does work for me but has the side effect of making me drowsy.
Of course efficacy can vary. But since OP's husband has never set on a cruise ship though, it seems premature to assume it would be ineffective for him, especially if he brings a variety of remedies. And obviously, when the ship is really rocking, even the bonine doesn't work, and I have to go have a lie down and throw up sometimes. We use all the other mitigations I mentioned above too to make it acceptable for me--I'll never be able to make a transatlantic or pacific sailing, but in the caribbean or bahamas any discomfort is short lived.
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I hate to hear that 
