Bonine's active ingredient is
meclizine. The same active ingredient is in
Dramamine All Day Less Drowsy. Note that as a chewable Bonine has aspartame in it and for some people that is an issue. Dramamine All Day Less Drowsy tablets do not have aspartame.
Dramamine Original Formula's active ingredient is
Dimenhydrinate 50mg. They have a tablet version (no aspartame) and chewable versions (adults and kids; both versions have aspartame).
In my experience, Dramamine Original Formula is more effective at dealing with active motion sickness, BUT the trade-off for me is it makes me really sleepy (sometimes to the point of must-take-a-nap, though not always).
I find in most cases the Less Drowsy strikes a good balance between effectiveness and drowsiness, and at least for me is a LOT less drowsy-making.
I get motion sickness when I cruise. Guaranteed. For the entire duration of the cruise I use a combination of Dramamine Less Drowsy and continuously worn SeaBands (actual brand name ones, not a knock off). I bring an extra couple pairs of SeaBands in case something happens to the ones I am wearing. I drink lots of ginger ale and I have ginger snaps I bring from home (see below). EVEN THEN I will still have symptoms -- they just for me are usually reduced to an "annoying" level as opposed to a "interfering with doing things" level, most of the time. On both of our
DCL cruises we had to sail around storms or through their edges -- it was rough enough that I had trouble walking in the halls and fell into a display in one of the stores (fortunately it was stuffed animals) and overnight many things fell off shelves in the stores) -- those nights I took a stronger anti-nausea med.
The company that makes Dramamine also makes an awesome product now: Dramamine® Non-Drowsy Naturals. They are ginger-containing gel caps, with a fixed dose of ginger. The company webpage about them is here: http://www.dramamine.com/motion-sickness-medicine/non-drowsy-naturals/ I find them VERY VERY effective in providing relief.
Other things I use: ginger ale (I like Canada Dry brand, and it actually contains ginger; not all ginger ale's actually contain ginger); ginger snap cookies (some are better than others -- my favourite is ShaSha ginger snaps:
http://www.shashabread.com/products/original-ginger-snaps ). Usually if I cannot tolerate eating anything else because of nausea (due to whatever cause) I can manage ginger ale and ginger snaps .
There are also prescription options which your doctor can discuss with you what is appropriate or not for you.
SW