I took it for a little over a year about 10 years ago. I don't remember the dosage -- I do remember the doc saying that he personally thought the initial recommended dose was way too high and always started people on half that, and the numbers people talk about now seem to be more like what I was probably taking (50?) so maybe everybody else decided the same thing he did!
The only side effects I experienced were dry eyes (had to stop wearing contacts) and some insomnia (I would fall asleep easily but wake up a few hours later and be unable to go back to sleep). He gave me another med to take when that happened, but I really tried to avoid taking it, probably foolishly.
Both side effects paled in comparison to the benefits I got from the drug -- it started working within 3 days for me (I know the norm is 6 weeks) and it was like the weight of the world came off my shoulders.
I had no problem tapering down and off it at all.
If I ever fall into clinical depression again, I'd take it again in a heartbeat, and if I had had to stay on it for life, I would have done so happily.