We have flown into TPA on our last two trips in 2007 and 2008. Since we are a family of 3, I usually save enough money to justify the car rental.
We rent from National using a code from this list found on FatWallet...
http://www.fatwallet.com/forums/travel-deals/788985
I was able to rent a full size vehicle for $18 each way ($23 after taxes/fees) for our February 2008 trip...probably because it was off season. I usually pay around $30 each way ($36 after taxes/fees). I pick up at TPA and drop off at the Dolphin.
Use the information and link on Mousesavers.com to join the Emerald Club for free. You can then bypass the counter in Tampa. When you return the vehicle to the Dolphin, the Valet takes the keys and gives you a return ticket...so, you bypass the counter again. The valet/return is right down the sidewalk (maybe 200 feet?) from the bus stop to catch a bus to any park or to DTD.
We usually fly into Tampa and drive to WDW. Once we check-in, we take the car to Wal-Mart for a grocery bill (bottled water, snacks, breakfast stuff, etc) and then grab a bite to eat offsite. The next morning, we hop in the car ready to go to the park. We return the car and catch a bus from the Dolphin to the park we are visiting that day.
You probably won't be able to do a car for less than $50 each way, though....but, I did like the convenience of having the car at the beginning of the trip to grab some groceries and the end of our trip to hit the outlet for souvies....
For the February 2008 trip, we saved a ton of money. The prices out of New Orleans during Mardi Gras were ridiculous. We paid almost $100 cheaper per person to fly into Tampa and then had that cheap $23 each way car rental.
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