I recently drove from Windsor which is a little closer, but I had 3 kids with me (DS10,DS3 and DS3months) so I had to take my time. We stayed in Cleveland, TN the first night and stopped in Tifton, GA the 2nd night. Our 3rd day of driving was a short trip from Tifton to Orlando and we felt pretty well-rested. If you stay in Tifton, GA I highly recommend the Comfort Inn right off I-75 (I can't remember what exit). It's brand new with beautiful rooms and pretty reasonable room rates. It was our favourite hotel of the whole trip. On the way home we stopped in Macon, GA and Cincinnatti, OH.