Honestly, that drive freaks me out nowadays.
In college I used to go from Tacoma to Santa Cruz in 12 hours, no problem, despite the continual construction in the Siskyous.
But we did that same drive in September, and I was just freaked out the whole way, no matter who was driving. I'm not saying I won't do it anymore, but I won't do it on a time schedule anymore! And I highly highly doubt I'll ever do it when the chance of snow is there.
Dukland's post reminded me of that horrible incident in the '06/'07 winter season where the family was going from Seattle to SF, took a road going east/west to get from the coast to I-5 or the reverse, got lost and stuck, and the husband ended up dying.

If you're going when there's any chance of snow, don't take shortcuts unless you KNOW them, and carry emergency provisions with you.
As for getting from the Bay Area to Anaheim, that drive took us SO long. We were told by multiple intelligent people that it would take 5 or 7 hours (I can't remember which one it was, but either one, it was consistent from *everyone*), going on either 101 or 5. Well I don't know what time-space vortex we went through, but with one bathroom break and stopping for lunch at Andersen's split pea soup restaurant, it took us 12. Checked in at PP after 7pm. So depressing. And SO weird.
On the way back up to the bay area, we had to stop at a hotel (Travel Lodge in Coalinga, which, by the way, is near a feed lot and therefore stinks to high heaven as the sun comes up and there are huge flies everywhere) b/c it was so dark by the time we got there and we were so tired.
So beware the vortices that suck away time, when on that very long trip.
