We have driven down almost every year for the last 7. We tend to drive straight through on the way to Orlando. Takes us 21 or 22 hours approx from Brockville. We stop long enough for gas, bathroom breaks and fast food drivethru. Coming home we leave quite early 6:00 AM or so and drive as far as Pennsylvania where we usually stop for the night and leave early again the next morning to get home in early afternoon. For years the route we took was 401 to the 1000 Islands bridge, I81 to I66 to I95 and then all the way south on I95. Last year we changed it a bit and went I81 to I 77 to I 26 to I95 and south from there. There did not seem to be as much truck traffic and was a more pleasant drive.
John