I have been to many many cities and know what I like and I don't.
Everytime I have gone to Chicago, I have gotten terribly horribly lost, and was always late for every seminar. The airports are busy, and its just not what I like.
I lived in NJ for 19 years, I know what Dana is saying as well. In fact we are reconsidering a move back there, so I have heard it all well... you want to move where? Why? Personally my family is there, and Southern New Jersey is much much different than North Jersey. I have found in my unscientifical research that people think of NJ, they think on Northern NJ, instead of S. NJ.
My parents live in the middle of the Pine Barrens in an isolated part of S. Jersey... I can't tell you how many people have asked me if it is near Newark..

(Its almost three hours away!)
It doesn't bother me when people knock Philadelphia, or even my specific suburbian area (The Main Line). I know what is mostly said isn't true, and there are some things that are... I am embarassed at some reflections of the city, and what has happened in the past...
I have also lived in Cleveland OH yes the "mistake by the lake". I can't tell you how many relatives of mine still asked if the lake was on fire in 1995 (they don't get out much). I loved Cleveland, the people were amazing, and the city itself was beautiful, compact, and the spirit was thriving.
I've been to Columbus as well, I know that it isn't all cornfields...