I logged into my college off-campus access. I didn't spend hours, but did search a little thoroughly. I didn't find ANY research confirming this adverse effect.
Perhaps studies haven't been done yet? I have never bought this stuff, but I can say the effectiveness against plaque was proven in the scholarly journals...I would rather have a little staining between my teeth, as long as I am reducing harmful plaque!
Actually the Crest Pro-Health Rinse causes stains in between the teeth and all along the gumline. It is very unsightly.
As for the scientific research:
1. The main active ingredient in the Crest Pro-Health Rinse is CPC, which has long been known to cause tooth staining and discoloration. Attached is a link to a position paper by the Canadian Dental Hygienists Association, which states the following (see page 6):
"CPC shares some of the adverse effects of CHX including tooth staining, burning, and increased calculus formation."
CDHA position paper
There are several scientific papers that have established the link between CPC and staining/discoloration. Two such papers listed in the CDHA report are as follows:
Mandel ID, Chemotherapeutic agents for controlling plaque and gingivitis, J Clin Periodontal, 1988, 15(8):488-98.
Mandel ID, Antimicrobial mouthrinses: overview and update, Journal of American Dental Association, 1994, 125 (Suppl 2):2S-10S.
2. There are a few other OTC mouthrinses that contain CPC (most notably Cepacol), but the new Crest Pro-Health Rinse contains 40% more CPC than the existing brands. See page 4 of the CDHA position paper for a comparison.
3. There is anecdotal evidence that this higher concentration of CPC in the Crest Rinse (an ingredient which is known to cause staining) is resulting in a high incidence of actual staining and discoloration. I already mentioned the
Amazon and Drugstore.com reviews. Also, there are several comments on the DentalTown and HygieneTown websites (I can provide some of the specific comments if you like) from Dentists and RDH's describing the severe staining from several pts who used the Crest rinse. These patients were otherwise healthy individuals who were not simultaneously using CHX or being treated for gum disease.
Lastly, I would just note that it is important, IMO, to use dental hygiene products that have been approved by the American Dental Association. Crest Pro-Health Rinse has NOT been approved by the ADA. Several good mouthrinses are available with the ADA seal. Listerine is one such product, but there are several others.
Again, all I'm saying is do a little research before you use the Crest rinse. If you still decide to use it, fine, just make sure you are aware of the possibility for significant tooth discoloration. I've seen it first hand, and it is nasty.