I'm an admitted germophobic! I too carry Clorax wipes, peel the bedspread off, wipe down doorknob, telephone and sinks and toilets. I bring cleaning gloves with me. Wipe out the draws, and the light swithces. and reclean the tub (little daughter takes bathes). I'm in the business.. so I know what doesn't get done.... Bedspreads are changed usually when a guest complains about stains! The rags used in your room to clean your sink, tub and toilet.. did just that all with 1 rag and just cleaned 20 other rooms with the same. YES... reclean your room upon check in... though it may LOOK clean... germs are lurking ALL over!