We were in 8100 (aft) and loved it. It's a handicapped room so there was extra space with a huge veranda. An awesome room! And, I think aft is more quiet. As far as the rough seas part, we didn't have an especially rough trip so it's hard to tell. But on days that were a little rougher, it seemed fine. I have been told the opposite, that the front is where you don't want to be in rough waters. In my opinion, just put me on the ship...all locations are great for one reason or another.
Have fun!