Anywhere from an hour to almost two hours, depending on the traffic (Busch Gardens is inside the city, so rush hour really can affect your drive). There are two popular ways to go depending where you get your directions - I-4 to Hillsborough Ave to 56th St. to Busch Blvd to McKinley Drive, and I-4 to I-75 to Fowler Ave to McKinley Drive. If you are arriving on a weekday during rush hour time (7 am to 9 am) take the second option. (Believe me, I really know this, I live a mile from BG!)