Accessibility is tricky because there are multiple kinds of accessible rooms, hearing, roll in shower, and so on. Combine that with all the views, and there might be only a room or two (or zero) that meets your needs in any particular booking category. So even if studios aren't gone in general, the accessible room can be booked (or not exist) and you are out of luck. If accessibility is important, you ned to make a choice with the numbers to support that. If you must have an accessible studio, then somewhere with tight studio availability, like CCV/BC/BW, probably not a great idea.
VGF2 has a lot of accessible rooms, but it also now has five studio booking categories. Combine that with multiple accessibility categories, and this could be dicey to actually book, or it might cost you points because you can only get some category you didn't want.
The obvious choice to me would be Poly. It has hundreds of studios in the standard view category, and multiple in each accessibility category. Also, the TTC boat next door is the easiest for accessibility. It's wonderful.
My other choice would be AKL. Kidani is just so big, there are a lot of rooms, and not a ton of categories. But then you are dealing with AK buses.
OKW/SSR also probably not a problem to book accessible, but I have no interest in those properties.