I wipe down the remote, phone, handles and surfaces in any hotel we stay at. My sister had a summer job working at a fancy hotel one summer during college, and I've heard the horror stories.
I love mouse keeping! It was very pleasant returning to a tidy room, with hand towels folded nicely over the faucets and towel animals left for us. These were nice little touches that made the stay a bit more magical. We always left a tip each morning and I wrote a little thank-you note on the last day.
I feel badly for the maids who have to clean up after a week's worth of mess. If you're generally neat, it might not be so bad, but if people have been partying, and the place is a shambles, then I hope they leave a generous tip!