Wow, I didn't realize there were so many from ROC!
We both went to college in Rochester (RIT) and stayed... that was 27 years ago. Before that we both grew up in upstate NY, so can't really give you an outside perspective. I grew up in a more snow bound area not too far away (Oswego). Specifically, we live in Honeoye Falls which is just on the southern suburban edge of Rochester.
Positives: Great schools and colleges. The arts. Golf. Hockey. The seasons. Wonderful summers and beautiful falls. Great health care. Fairly high tech population. No hurricanes, tornadoes, forest fires, or earthquakes.
Negatives: I refer to it as 'The PermaCloud'. It rolls in Mid-November and doesn't leave until March. The nasal sound that creeps into your speech. TAXES!!! - Really, have you looked at them?
Happy to answer any questions if you have any.