Ok, so flying an airbus is VERY VERY different from flying a Boeing aircraft. Airbus planes are designed statically unstable. This means, it is extremely difficult for the pilot to control it. So Airbus has a computer system that runs it. There safety design is that the computer system is 4 times redundant. Now Boeing aircraft are designed statically stable. The pilot can control the aircraft if they loose their computer system. So far, going through the terrorist lives and what they did before September 11, they only found training on an Boeing simulators.
Also, the fact that the airbus lost an engine. Either way this is a tradegy!
addition: I should note that I am an engineer NOT a pilot. This is what I have learned in classes and from co-workers. I would love for a pilot to confirm this, or correct me. My initial contribution was just my gut feeling. Originally CNN was reporting it was a Boeing 767 and my heart sank. When they said it was an Airbus, I have to admit, I was relieved.