Zolpidem
Brand names: Ambien®, Hypnogen®, Myslee®, Nimadorm®, Nitrest®, Sanval®, Stilnoct®, Stilnox®, Zoldem®, Zolfresh®, Zolt®
Formula: C19H21N3O
Half life: ~ 2 - 2.6 hours
Single unit dose: Unknown
Recommended outpatient dose: 10mg [Verified]
Maximum outpatient dose: 10mg [Verified]
Prescribed to fight insomnia in the short term only, prolonged use can cause tolerance to build up, causing the effectiveness of the drug to decline. It works very quickly (usually within 10 to 20 minutes) and has a short half life. Interestingly, the USA army prescribed the drug to pilots to aid their sleep between missions, allowing them to recoup their lost energy. Off-label, Zolpidem is used to combat restless legs syndrome and there is anecdotal evidence that it can help in cases of persistent vegetative states. At ten times the normal dose Zolpidem acts as a anticonvulsant and at twenty times the normal dose it acts as a muscle relaxant; these two uses are never applied, due to the manifestation of side effects at such high doses, such as hallucinations. Side effects may include anterograde amnesia, hallucinations, delusions, ataxia, euphoria or dysphoria, increased appetite, decreased libido and impaired judgement/reasoning; upon cessation of treatment, patients my be subject to rebound insomnia. Be warned: this drug has been shown to cause cancer in some patients.