Absolutely go solo, you'll have a great time! I've done it several times myself, have DVC and a quick getaway is always in the mix. Like others have said, solo at Disney is not really solo. Staying at the EPCOT resorts I think makes it a bit easier and in my opinion more enjoyable. I once stayed at SSR and while on the way to Downtown Disney met a great couple on the boat, ended up having dinner with them. People are generally friendly especially those with DVC, they seem to have a more laid back approach.
My next trip is for 10 days in September, the last 4 I'll be solo. First week is at OKW in a 1 BR and the last 3 nights I'dm moving to a studio at the BCV.
Go and have fun, maybe you'll meet the next Mrs while your there!