Things that worked for me:
Therapy. (it's just good sense to have a professional to help you with a mental issue, isn't it? )
Medication - very low dose (made me feel more relaxed in social situations and once I was "better" I didn't need it anymore.)
Vacation - I went someplace where I didn't know people so I didn't have that mental conversation "OH GOD WHAT IF XXXXX FINDS OUT I SAID SOMETHING STUPID!!!")
Just out of curiosity, what medication did you take? Also, did you have to take it every day or only as needed? I'm completely inept socially and have tried practically everything - except medication and therapy. Therapy because of the obvious - I don't like interacting with people. And I do tend to self-medicate with alcohol or xanax but neither really helps. They do make me more relaxed but they don't help with the other issues and probably make things worse.
I've gotten to the point where I've resigned myself to the fact that this is just the way it is for me. I'm actually much happier now that I'm not constantly trying to be someone I'm not; however I'm afraid when the kids move out I'm going to be very lonely and this situation will no longer be acceptable.