We've driven from Maine quite a few times and have gone a few different ways and I would agree with Dan about the Route he suggested.
Don't know if your husband is a "white knuckle" driver when it comes to lots of traffic, I know mine is when we go through the DC area or Garden State Parkway. We found that we added a bit of driving to our schedule but enjoyed driving much more through PA to Virginia which was very colorful and less stressful. BTW...my husband hates the Francis Scott Key bridge, thought it was too narrow and swore he would NEVER drive it again.
Nancy