Thank you everyone for your input and suggestions! I have made a tentative decision to base ourselves at Manhattan Beach for our first 3 nights. It's a little bit quieter so a little bit cheaper. It's also away from the Hollywood hustle and bustle, which I'm happy to go and see but didn't really want to stay amongst.
So now we will spend 3 nights Manhattan Beach, 2 nights Anaheim. I've also changed our GC accom. We are now just going to stay one night in Tusayan and see the GC. Then we are going to drive to Phoenix via Sedona during the day and stay at an airport hotel overnight before our 10am flight to MCO. I was concerned about leaving Tusayan at 3am in the morning and negotiating potentially slippery roads, animals and Phoenix traffic to be at the airport for a 10am flight. I think getting there the night before will be less stressful.
I've also canned the All Star Sports segment of our WDW stay. We are just going to stay at POR the entire time now. I wasn't particularly happy about staying at a value resort. Fingers crossed POR lives up to our expectations!