P.E. (gym) was my #1 for sure. I think I only had to take it for two years in high school though.
Other than that, it was definitely the sciences. I hated biology, chemistry, and physics. I liked marine biology though because the teacher made it fun.
I loved all of the language arts type classes-- English, history, government, and especially foreign languages. I used all of my electives for foreign languages, so I took German, French, and Spanish.