To add to the above, remember that in a 2 bedroom dedicated, the second bedroom has two queen size beds.
In a 2 bedroom lock-off, the second room, which is really just a Studio opened up to a 1 bedroom villa, has a king size bed and a sofabed layout. It also then offers a small food prep area with microwave, toaster, etc.
DW and I have never found that the 2 bedroom lock-off worked for us, as we all share in the kitchen and living room areas of the villa, and everyone travelling with us appreciates a "real" bed.