<font color=navy>LAX - San Diego ---
The best way is to get on the 405 - two ways to do that
As you leave the LAX horseshoe, stay to your right, and take Sepulveda South. That will take you to the 105 East. Get on the 105 fwy East. The ramp to the 405 south is just up ahead off of the 105.
If you miss the turn-off for Sepulveda South, take Century Blvd. East, and a couple of miles down the road, you'll see a sign to take the 405 south.
The 405 ends at the 5, which will take you all the way to San Diego.
So:
405 fwy south - 5 fwy south (about 2 - 2.5 hours, depending on traffic)
To get to
Disneyland from San Diego -- just take the 5 north all the way to the Disneyland Resort exit. (about 1.5-2 hours)